Nosso Laboratório

Pesquisa em Apicomplexa

O Laboratório de Pesquisa em Apicomplexa foi criado em 2018, tendo como o foco principal de pesquisa a investigação dos mecanismos moleculares e imunológicos de parasitas Apicomplexas, usando como modelo as espécies T. gondii, causador da toxoplasmose e Plasmodium spp., causador da malária.

Linhas de pesquisa

Últimas Publicações

  • Modulation of Virulence Factors during Trypanosoma cruzi Differentiation.Oliveira, C; Holetz, FB ; Alves, LR ; Ávila, AR. Modulation of Virulence Factors during Trypanosoma cruzi Differentiation. PATHOGENS, 2023.
  • Offering technologies for innovation: strategies and challenges.
    Goebel, K; Losekann, SD ; Polla, PTB; Montenegro, KBM; Ávila, AR. Offering technologies for innovation: strategies and challenges. Innovation & Management Review, , 2023.
  • Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis.Dos Santos, DA; Souza, HFS; Silber, AM; Souza, TDACBD ; Ávila, AR. Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis. Frontiers in Cellular and Infection Microbiology, 2023.
  • A Unique Deacetylase of Toxoplasma Apicoplast.Fragoso, MSI; De Siqueira, CM; Vitorino, FNL; Vieira, AZ; Martins-Duarte, ÉS; Faoro, H; Da Cunha, JPC; Ávila, AR; Nardelli, SC. TgKDAC4: A Unique Deacetylase of Toxoplasma Apicoplast. Microorganisms,  2023.
  • Plasmodium vivax transcriptomics: What is new?Ferraboli JW; Da Veiga GTS;  Albrecht L. Plasmodium vivax transcriptomics: What is new? Exp Biol Med (Maywood). 2023 Oct;248(19):1645-1656.  doi: 10.1177/15353702231198070. Epub 2023 Oct 3.
  • Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein.Matos, ADS; Soares, IF; Baptista BDO; De Souza HAS; Chaves LB;  Perce-Da-Silva, DS; Riccio, EKP; Albrecht, L; Totino, PRR; Rodrigues-Da-Silva RN; Daniel-Ribeiro CT;  Pratt-Riccio, LR; Da Costa Lima-Junior, J. Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein. Int J Mol Sci  2023 Jul 18;24(14):11571. doi: 10.3390/ijms241411571.

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Laboratório de Pesquisa em Apicomplexa