Publicações

2019

 

Human Heart Explant-Derived Extracellular Vesicles: Characterization and Effects on the In VitroRecellularization of Decellularized Heart Valves.
Leitolis A1, Suss PH2, Roderjan JG3, Angulski ABB4, da Costa FDA5, Stimamiglio MA6, Correa A7.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Human+Heart+Explant-Derived+Extracellular+Vesicles%3A+Characterization+and+Effects+on+the+In+Vitro+Recellularization+of+Decellularized+Heart+Valves

Structural assessments in decellularized extracellular matrix of porcine semilunar heart valves: Evaluation of cell niches.
Roderjan JG1, de Noronha L2, Stimamiglio MA3, Correa A3, Leitolis A3, Bueno RRL4, da Costa FDA5.
https://www.ncbi.nlm.nih.gov/pubmed/30770594
The skin regeneration potential of a pro-angiogenic secretome from human skin-derivedmultipotent stromal cells.
Robert AW1, Azevedo Gomes F2, Rode MP2, Marques da Silva M2, Veleirinho MBDR2, Maraschin M2, Hayashi L2, Wosgrau Calloni G2, Stimamiglio MA1.
https://www.ncbi.nlm.nih.gov/pubmed/?term=The+skin+regeneration+potential+of+a+pro-angiogenic+secretome+from+human+skin-derived+multipotent+stromal+cells
Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes.
Pereira IT1, Spangenberg L2, Robert AW1, Amorín R2, Stimamiglio MA1, Naya H2, Dallagiovanna B3.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Cardiomyogenic+differentiation+is+fine-tuned+by+differential+mRNA+association+with+polysomes
Cell cycle genes are downregulated after adipogenic triggering in human adipose tissue-derived stem cells by regulation of mRNA abundance
Bruna H. Marcon, Patrícia Shigunov, Lucia Spangenberg, Isabela Tiemy Pereira, Alessandra Melo de Aguiar, Rocío Amorín, Carmen K. Rebelatto, Alejandro Correa & Bruno Dallagiovanna
https://www.ncbi.nlm.nih.gov/pubmed/?term=Cell+cycle+genes+are+downregulated+after+adipogenic+triggering+in+human+adipose+tissue-derived+stem+cells+by+regulation+of+mRNA+abundance
The inhibition of adipogenesis via an in vitro assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method
Ana Paula RessettAbudaCriscieleKuligovskiaNatássia Caroline ResendeCorrêaa1Elizabeth Cunha Pennade MoraesabRodrigo Rêgo BarrosCarusoacDesirée CigaranSchuckdCarla AbdoBrohemdBrunoDallagiovannaaAlessandra Melode Aguiara
https://www.ncbi.nlm.nih.gov/pubmed/?term=The+inhibition+of+adipogenesis+via+an+in+vitro+assay+can+reduce+animal+use+by+more+precisely+estimating+the+starting+dose+for+the+acute+toxic+class+method
Cardiomyogenesis Modeling Using Pluripotent Stem Cells: The Role of Microenvironmental Signaling
Amanda Leitolis*†, Anny W. Robert*†, Isabela T. Pereira*†, Alejandro Correa and Marco A. Stimamiglio
https://www.frontiersin.org/articles/10.3389/fcell.2019.00164/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Cell_and_Developmental_Biology&id=475896
2018

 

In vitro evaluation of bovine pericardium after a soft decellularization approach for use in tissueengineering.

https://www.ncbi.nlm.nih.gov/pubmed/?term=In+vitro+evaluation+of+bovine+pericardium+after+a+soft+decellularization+approach+for+use+in+tissue+engineering
Heuschkel MA1, Leitolis A1, Roderjan JG2, Suss PH2, Luzia CAO2, da Costa FDA2, Correa A1, Stimamiglio MA1.

Expanded CD133+ Cells from Human Umbilical Cord Blood Improved Heart Function in Rats afterSevere Myocardial Infarction.

Correa A1, Ottoboni GS2, Senegaglia AC2, Capriglione LGA2, Miyague NI2, Leite LMB2, Jamur VR2, Rebelatto CLK2, Olandoski M2, Brofman PRS2
Stem Cells Int. 2018 Apr 11;2018:5412478. doi: 10.1155/2018/5412478
https://www.ncbi.nlm.nih.gov/pubmed/?term=Expanded+CD133%2B+Cells+from+Human+Umbilical+Cord+Blood+Improved+Heart+Function+in+Rats+after+Severe+Myocardial+Infarction

Gene expression analysis of human adipose tissue-derived stem cells during the initial steps of in vitro osteogenesis.

Robert AW1, Angulski ABB1, Spangenberg L2, Shigunov P1, Pereira IT1, Bettes PSL3, Naya H2, Correa A1, Dallagiovanna B1, Stimamiglio MA4.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+expression+analysis+of+human+adipose+tissue-derived+stem+cells+during+the+initial+steps+of+in+vitro+osteogenesi

Human T Lymphocytes Are Permissive for Dengue Virus Replication.
Silveira GF1, Wowk PF1, Cataneo AHD1, Dos Santos PF2, Delgobo M2, Stimamiglio MA3, Lo Sarzi M4, Thomazelli APFS5, Conchon-Costa I5, Pavanelli WR5, Antonelli LRV6, Báfica A2, Mansur DS2, Dos Santos CND7, Bordignon J7.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Human+T+Lymphocytes+Are+Permissive+for+Dengue+Virus+Replication

Perspectivas e desafios regulatórios no uso de células-tronco em métodos alternativos ao uso de animais

Cintia Delai da Silva Horinouchi ,Ana Paula Ressetti Abud ,Ariane Caroline Paschoal, Crisciele Kuligosviski, Thamile Luciane Reus, Bruno Dallagiovanna Muniz, Alessandra Melo de Aguiar
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1076

 

Polysome profiling followed by RNA-seq of cardiac differentiation stages in hESCs.

Pereira IT1, Spangenberg L2, Robert AW1, Amorín R2, Stimamiglio MA1, Naya H2, Dallagiovanna B1.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Polysome+profiling+followed+by+RNA-seq+of+cardiac+differentiation+stages+in+hESCs

2017

 

5 - Mesenchymal Stem/Stromal Cells as Biological Factories

A.B.B.Angulski,A.Correa, M.A.Stimamiglio
https://www.sciencedirect.com/science/article/pii/B9780128031025000057?via%3Dihub  

 

Internal control for realtime polymerase chain reaction based on MS2 bacteriophage for RNAviruses diagnostics.
Zambenedetti MR1,2, Pavoni DP1, Dallabona AC1, Dominguez AC1, Poersch CO1, Fragoso SP1, Krieger MA1,3.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Internal+control+for+real-time+polymerase+chain+reaction+based+on+MS2+bacteriophage+for+RNA+viruses+diagnostics

The Protein Content of Extracellular Vesicles Derived from Expanded Human Umbilical CordBlood-Derived CD133+ and Human Bone Marrow-Derived Mesenchymal Stem Cells PartiallyExplains Why both Sources are Advantageous for Regenerative Medicine.

Angulski AB1, Capriglione LG2, Batista M1, Marcon BH1, Senegaglia AC2, Stimamiglio MA3, Correa A4.
https://www.ncbi.nlm.nih.gov/pubmed/?term=The+Protein+Content+of+Extracellular+Vesicles+Derived+from+Expanded+Human+Umbilical+Cord+Blood-Derived+CD133%2B+and+Human+Bone+Marrow-Derived+Mesenchymal+Stem+Cells+Partially+Explains+Why+both+Sources+are+Advantageous+for+Regenerative+Medicine

Tissue Derived Signals for Mesenchymal Stem Cell Stimulation: Role of Cardiac and UmbilicalCord Microenvironments.

Robert AW1, Schittini AVMarchini FKBatista MAffonso Da Costa MBSenegaglia ACBrofman PRAbud APStimamiglio MA.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Tissue-Derived+Signals+for+Mesenchymal+Stem+Cell+Stimulation%3A+Role+of+Cardiac+and+Umbilical+Cord+Microenvironments

lncRNAs are associated with polysomes during adipose-derived stem cell differentiation.

Dallagiovanna B1, Pereira IT2, Origa-Alves AC3, Shigunov P4, Naya H5, Spangenberg L6.
https://www.ncbi.nlm.nih.gov/pubmed/?term=lncRNAs+are+associated+with+polysomes+during+adipose-derived+stem+cell+differentiation

Downregulation of the protein synthesis machinery is a major regulatory event during earlyadipogenic differentiation of human adipose-derived stromal cells.

Marcon BH1, Holetz FB1, Eastman G2, Origa-Alves AC1, Amorós MA3, de Aguiar AM1, Rebelatto CK4, Brofman PRS4, Sotelo-Silveira J5, Dallagiovanna B6
https://www.ncbi.nlm.nih.gov/pubmed/?term=Downregulation+of+the+protein+synthesis+machinery+is+a+major+regulatory+event+during+early+adipogenic+differentiation+of+human+adipose-derived+stromal+cells

2016  

Secretome from resident cardiac stromal cells stimulates proliferation, cardiomyogenesis and angiogenesis of progenitor cells.
Reus TL1, Robert AW2, Da Costa MB3, de Aguiar AM4, Stimamiglio MA5.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Secretome+from+resident+cardiac+stromal+cells+stimulates+proliferation%2C+cardiomyogenesis+and+angiogenesis+of+progenitor+cells

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